Cargando…

2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, (18)F-Labeling and Preclinical PET Imaging

The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar derivatives—mimicking nucleosides—have proven the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maier, Florian C., Schweifer, Anna, Damaraju, Vijaya L., Cass, Carol E., Bowden, Gregory D., Ehrlichmann, Walter, Kneilling, Manfred, Pichler, Bernd J., Hammerschmidt, Friedrich, Reischl, Gerald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469291/ https://www.ncbi.nlm.nih.gov/pubmed/30781409 http://dx.doi.org/10.3390/ph12010031

Ejemplares similares

Preparation of Nucleosides Derived from 2-Nitroimidazole and d-Arabinose, d-Ribose, and d-Galactose by the Vorbrüggen Method and Their Conversion to Potential Precursors for Tracers To Image Hypoxia
por: Schweifer, Anna, et al.
Publicado: (2011)

Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [(18)F]-fluoro-azomycinarabino-furanoside ([(18)F]FAZA)
por: Maier, Florian C, et al.
Publicado: (2011)

Efficient preparation of 2-nitroimidazole nucleosides as precursors for hypoxia PET tracers
por: Križková, Petra, et al.
Publicado: (2016)

A Comparative pO(2) Probe and [(18)F]-Fluoro-Azomycinarabino-Furanoside ([(18)F]FAZA) PET Study Reveals Anesthesia-Induced Impairment of Oxygenation and Perfusion in Tumor and Muscle
por: Mahling, Moritz, et al.
Publicado: (2015)

Noninvasive Detection of Smooth Muscle Cell-Derived Hot Spots to Study Atherosclerosis by PET/MRI in Mice
por: Feil, Susanne, et al.
Publicado: (2023)

Investigation of acetyl migrations in furanosides
por: Chevallier, O P, et al.
Publicado: (2006)

Biological reduction of nitroimidazole-functionalized gold nanorods for photoacoustic imaging of tumor hypoxia
por: Umehara, Yui, et al.
Publicado: (2019)

Driving Force of the Pyranoside-into-Furanoside Rearrangement
por: Gerbst, Alexey G., et al.
Publicado: (2019)

(68)Ga‐nitroimidazole PET/CT imaging of hypoxia in tuberculosis: A case series
por: Bresser, Philippa L, et al.
Publicado: (2022)

Twenty Years of Mycobacterial Glycans: Furanosides and Beyond
por: Lowary, Todd L.
Publicado: (2016)

Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent “Pimonidazole” in Hypoxia
por: Masaki, Yukiko, et al.
Publicado: (2016)

Imaging latent tuberculosis infection with radiolabeled nitroimidazoles
por: Ankrah, Alfred O., et al.
Publicado: (2016)

Preclinical Identification Of Tumor-Draining Lymph Nodes Using a Multimodal Non-invasive In vivo Imaging Approach
por: Knopf, Philipp, et al.
Publicado: (2023)

A New, Potent 2‐Nitroimidazole Nucleoside Hypoxic Cell Radiosensitizer, RP170
por: Sasai, Keisuke, et al.
Publicado: (1989)

Synthesis and Preliminary Evaluation of a Novel (18)F-Labeled 2-Nitroimidazole Derivative for Hypoxia Imaging
por: Lu, Jing, et al.
Publicado: (2021)

Synthesis of 4-thiol-furanosidic uronate via hydrothiolation reaction
por: Ma, Shih-Ting, et al.
Publicado: (2021)

Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using (64)Cu-labeled antibodies in a neuroblastoma mouse model
por: Maier, Florian C., et al.
Publicado: (2016)

Synthesis and Biological Evaluation of a New Nitroimidazole-(99m)Tc-Complex for Imaging of Hypoxia in Mice Model
por: Zhang, Qing, et al.
Publicado: (2016)

Synthesis and Evaluation of (99m)Tc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging
por: Ruan, Qing, et al.
Publicado: (2023)

Influence of per-O-sulfation upon the conformational behaviour of common furanosides
por: Gerbst, Alexey G, et al.
Publicado: (2019)

Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents
por: Rashed, Faisal Bin, et al.
Publicado: (2022)

Preparation and Bioevaluation of Novel (99m)Tc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia
por: Ruan, Qing, et al.
Publicado: (2021)

Highly Stereoselective Glycosylation Reactions of Furanoside Derivatives via Rhenium (V) Catalysis
por: Casali, Emanuele, et al.
Publicado: (2021)

Imaging fibrosis in inflammatory diseases: targeting the exposed extracellular matrix
por: Beziere, Nicolas, et al.
Publicado: (2019)

In vivo imaging of CD8(+) T cells in metastatic cancer patients: first clinical experience with simultaneous [(89)Zr]Zr-Df-IAB22M2C PET/MRI
por: Schwenck, Johannes, et al.
Publicado: (2023)

Chemosensitization by lipophilic nitroimidazoles.
por: Twentyman, P. R., et al.
Publicado: (1983)

Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins
por: Rashed, Faisal Bin, et al.
Publicado: (2021)

Synthesis of C-acyl furanosides via the cross-coupling of glycosyl esters with carboxylic acids
por: Wei, Yongliang, et al.
Publicado: (2021)

Oxo-Rhenium-Mediated Allylation of Furanoside Derivatives: A Computational Study on the Mechanism and the Stereoselectivity
por: Casali, Emanuele, et al.
Publicado: (2022)

Recent Advances of (68)Ga-Labeled PET Radiotracers with Nitroimidazole in the Diagnosis of Hypoxia Tumors
por: Nguyen, Anh Thu, et al.
Publicado: (2023)

The Role of Nitroreductases in Resistance to Nitroimidazoles
por: Thomas, Carol, et al.
Publicado: (2021)

Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells.
por: Parliament, M. B., et al.
Publicado: (1992)

Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole
por: Dhani, N C, et al.
Publicado: (2015)

Design and Synthesis of Vandetanib Derivatives Containing Nitroimidazole Groups as Tyrosine Kinase Inhibitors in Normoxia and Hypoxia
por: Wei, Huiqiang, et al.
Publicado: (2016)

Influence of 2-Nitroimidazoles in the Response of FaDu Cells to Ionizing Radiation and Hypoxia/Reoxygenation Stress
por: Rashed, Faisal Bin, et al.
Publicado: (2023)

Use of a high frequency ultrasound microscope to image the action of 2-nitroimidazoles in multicellular spheroids.
por: Bérubé, L. R., et al.
Publicado: (1992)

Stereocontrolled Debenzylative Cycloetherification Reaction as a Route to Enantiopure C-Furanosides with Amino Substituents in the Side Chain
por: Tiara, Karolina, et al.
Publicado: (2020)

Site-selective redox isomerizations of furanosides using a combined arylboronic acid/photoredox catalyst system
por: Dimakos, Victoria, et al.
Publicado: (2020)

How to Modulate Tumor Hypoxia for Preclinical In Vivo Imaging Research
por: De Bruycker, Sven, et al.
Publicado: (2018)

Proceedings of the Workshop on the Enhancement of Chemotherapy by Nitroimidazoles
Publicado: (1982)

Cannot write session to /tmp/vufind_sessions/sess_spm5jo40acdm8rifa3fvr5p158