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Metformin use and risk of cancer in patients with type 2 diabetes: a cohort study of primary care records using inverse probability weighting of marginal structural models

BACKGROUND: Previous studies provide conflicting evidence on whether metformin is protective against cancer. When studying time-varying exposure to metformin, covariates such as body mass index (BMI) and glycated haemoglobin (HbA1c) may act as both confounders and causal pathway variables, and so ca...

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Detalles Bibliográficos
Autores principales: Farmer, Ruth E, Ford, Deborah, Mathur, Rohini, Chaturvedi, Nish, Kaplan, Rick, Smeeth, Liam, Bhaskaran, Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469299/
https://www.ncbi.nlm.nih.gov/pubmed/30753459
http://dx.doi.org/10.1093/ije/dyz005