Neuroprotective effect of N-acetylcysteine against cisplatin-induced toxicity in rat brain by modulation of oxidative stress and inflammation

BACKGROUND: Neurotoxicity is a major obstacle to the effectiveness of cisplatin (CDDP) in cancer chemotherapy. Oxidative stress and inflammation are considered to be the major mechanisms involved in CDDP-induced neurotoxicity. The rationale of our study was to investigate the efficacy of N-acetylcys...

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Detalles Bibliográficos
Autores principales: Abdel-Wahab, Wessam M, Moussa, Farouzia I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469471/
https://www.ncbi.nlm.nih.gov/pubmed/31043768
http://dx.doi.org/10.2147/DDDT.S191240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469471/
https://www.ncbi.nlm.nih.gov/pubmed/31043768
http://dx.doi.org/10.2147/DDDT.S191240

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