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EGFP-EGF1-conjugated poly(lactic-co-glycolic acid) nanoparticles, a new diagnostic tool and drug carrier for atherosclerosis

BACKGROUND: EGFP-EGF1-conjugated poly(lactic-co-glycolic acid) (PLGA) nanoparticle (ENP) has a specific affinity to tissue factor (TF). The aim of this study was to investigate the target delivery of ENP to plaques and its uptake in a mouse model of atherosclerosis in vivo and in vitro. MATERIALS AN...

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Detalles Bibliográficos
Autores principales: Wu, Zhilin, Chen, Chen, Zhang, Bo, Tang, Liang, Shi, Wei, Liao, Danying, Di, Gaohong, Davis, Jacques RJ, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469482/
https://www.ncbi.nlm.nih.gov/pubmed/31043777
http://dx.doi.org/10.2147/IJN.S199695