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Supramolecular arrangement of the full-length Zika virus NS5

Zika virus (ZIKV), a member of the Flaviviridae family, has emerged as a major public health threat, since ZIKV infection has been connected to microcephaly and other neurological disorders. Flavivirus genome replication is driven by NS5, an RNA-dependent RNA polymerase (RdRP) that also contains a N...

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Detalles Bibliográficos
Autores principales: Ferrero, Diego S., Ruiz-Arroyo, Victor M., Soler, Nicolas, Usón, Isabel, Guarné, Alba, Verdaguer, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469808/
https://www.ncbi.nlm.nih.gov/pubmed/30951555
http://dx.doi.org/10.1371/journal.ppat.1007656