QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis

Dihydropteridine reductase (QDPR) catalyzes the recycling of tetrahydrobiopterin (BH(4)), a cofactor in dopamine, serotonin, and phenylalanine metabolism. QDPR-deficient patients develop neurological symptoms including hypokinesia, truncal hypotonia, intellectual disability and seizures. The underly...

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Detalles Bibliográficos
Autores principales: Breuer, Maximilian, Guglielmi, Luca, Zielonka, Matthias, Hemberger, Verena, Kölker, Stefan, Okun, Jürgen G., Hoffmann, Georg F., Carl, Matthias, Sauer, Sven W., Opladen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469847/
https://www.ncbi.nlm.nih.gov/pubmed/30995231
http://dx.doi.org/10.1371/journal.pone.0215162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469847/
https://www.ncbi.nlm.nih.gov/pubmed/30995231
http://dx.doi.org/10.1371/journal.pone.0215162

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