Chronic High-Fat Diet Exacerbates Sexually Dimorphic Pomc(tm1/tm1) Mouse Obesity

Mice with a targeted mutation in the pro-opiomelanocortin (Pomc) gene (Pomc(tm1/tm1) mice) are unable to synthesize desacetyl-α-MSH and α-MSH and they develop obesity when fed chow diet. In this study, we hypothesized that a chronic high-fat (HF) diet exacerbates Pomc(tm1/tm1) mouse obesity. Male an...

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Detalles Bibliográficos
Autores principales: Hubbard, Kristina, Shome, Avik, Sun, Bo, Pontré, Beau, McGregor, Ailsa, Mountjoy, Kathleen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469954/
https://www.ncbi.nlm.nih.gov/pubmed/30997487
http://dx.doi.org/10.1210/en.2018-00924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469954/
https://www.ncbi.nlm.nih.gov/pubmed/30997487
http://dx.doi.org/10.1210/en.2018-00924

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