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Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

Cell wall glycopolymers on the surface of Gram-positive bacteria are fundamental to bacterial physiology and infection biology. Here we identify gacH, a gene in the S. pyogenes Group A Carbohydrate (GAC) biosynthetic cluster, in two independent transposon library screens for its ability to confer re...

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Detalles Bibliográficos
Autores principales: Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Breton, Yoann Le, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M., Korotkova, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470023/
https://www.ncbi.nlm.nih.gov/pubmed/30936502
http://dx.doi.org/10.1038/s41589-019-0251-4