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Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides
Cell wall glycopolymers on the surface of Gram-positive bacteria are fundamental to bacterial physiology and infection biology. Here we identify gacH, a gene in the S. pyogenes Group A Carbohydrate (GAC) biosynthetic cluster, in two independent transposon library screens for its ability to confer re...
Autores principales: | Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Breton, Yoann Le, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M., Korotkova, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470023/ https://www.ncbi.nlm.nih.gov/pubmed/30936502 http://dx.doi.org/10.1038/s41589-019-0251-4 |
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