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Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of N-Methyl-D-Aspartate Receptors

BACKGROUND: This study investigated the role of NR2B in a modulated pain process in the painful diabetic neuropathy (PDN) rat using various pain stimuli. METHODS: Thirty-two Sprague-Dawley male rats were randomly allocated into four groups (n=8): control, diabetes mellitus (DM) rats and diabetic rat...

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Detalles Bibliográficos
Autores principales: Ismail, Che Aishah Nazariah, Suppian, Rapeah, Abd Aziz, Che Badariah, Haris, Khalilah, Long, Idris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470097/
https://www.ncbi.nlm.nih.gov/pubmed/30604591
http://dx.doi.org/10.4093/dmj.2018.0020