Myricetin Protects Against High Glucose-Induced β-Cell Apoptosis by Attenuating Endoplasmic Reticulum Stress via Inactivation of Cyclin-Dependent Kinase 5

BACKGROUND: Chronic hyperglycemia has deleterious effects on pancreatic β-cell function and turnover. Recent studies support the view that cyclin-dependent kinase 5 (CDK5) plays a role in β-cell failure under hyperglycemic conditions. However, little is known about how CDK5 impair β-cell function. M...

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Detalles Bibliográficos
Autores principales: Karunakaran, Udayakumar, Elumalai, Suma, Moon, Jun Sung, Jeon, Jae-Han, Kim, Nam Doo, Park, Keun-Gyu, Won, Kyu Chang, Leem, Jaechan, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470101/
https://www.ncbi.nlm.nih.gov/pubmed/30688049
http://dx.doi.org/10.4093/dmj.2018.0052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470101/
https://www.ncbi.nlm.nih.gov/pubmed/30688049
http://dx.doi.org/10.4093/dmj.2018.0052

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