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Early P2X7R-dependent activation of microglia during the asymptomatic phase of autoimmune encephalomyelitis

Microglia-mediated neuroinflammation accompanies many central nervous system (CNS) diseases, including multiple sclerosis (MS), and is strongly dependent on the purinergic P2X7 receptor. The nature of the inflammatory response in MS is studied for decades indicating, that proinflammatory microgliosi...

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Detalles Bibliográficos
Autores principales: Grygorowicz, Tomasz, Strużyńska, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470107/
https://www.ncbi.nlm.nih.gov/pubmed/30209761
http://dx.doi.org/10.1007/s10787-018-0528-3