Cargando…

Application of triple quadrupole mass spectrometry for the characterization of antibody–drug conjugates

Antibody–drug conjugates (ADCs) are an inherently heterogeneous class of biotherapeutics, the development of which requires extensive characterization throughout. During the earliest phases of preclinical development, when synthetic routes towards the desired conjugate are being assessed, the main i...

Descripción completa

Detalles Bibliográficos
Autores principales: Källsten, Malin, Pijnappel, Matthijs, Hartmann, Rafael, Lehmann, Fredrik, Kovac, Lucia, Lind, Sara Bergström, Bergquist, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470114/
https://www.ncbi.nlm.nih.gov/pubmed/30848315
http://dx.doi.org/10.1007/s00216-019-01699-0