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Application of triple quadrupole mass spectrometry for the characterization of antibody–drug conjugates
Antibody–drug conjugates (ADCs) are an inherently heterogeneous class of biotherapeutics, the development of which requires extensive characterization throughout. During the earliest phases of preclinical development, when synthetic routes towards the desired conjugate are being assessed, the main i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470114/ https://www.ncbi.nlm.nih.gov/pubmed/30848315 http://dx.doi.org/10.1007/s00216-019-01699-0 |