Comparison of the 3D structures of mouse and human α-synuclein fibrils by solid-state NMR and STEM()

Intra-neuronal aggregation of α-synuclein into fibrils is the molecular basis for α-synucleinopathies, such as Parkinson’s disease. The atomic structure of human α-synuclein (hAS) fibrils was recently determined by Tuttle et al. using solid-state NMR (ssNMR). The previous study found that hAS fibril...

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Detalles Bibliográficos
Autores principales: Hwang, Songhwan, Fricke, Pascal, Zinke, Maximilian, Giller, Karin, Wall, Joseph S., Riedel, Dietmar, Becker, Stefan, Lange, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470123/
https://www.ncbi.nlm.nih.gov/pubmed/29678776
http://dx.doi.org/10.1016/j.jsb.2018.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470123/
https://www.ncbi.nlm.nih.gov/pubmed/29678776
http://dx.doi.org/10.1016/j.jsb.2018.04.003

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