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Comparison of the 3D structures of mouse and human α-synuclein fibrils by solid-state NMR and STEM()
Intra-neuronal aggregation of α-synuclein into fibrils is the molecular basis for α-synucleinopathies, such as Parkinson’s disease. The atomic structure of human α-synuclein (hAS) fibrils was recently determined by Tuttle et al. using solid-state NMR (ssNMR). The previous study found that hAS fibril...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470123/ https://www.ncbi.nlm.nih.gov/pubmed/29678776 http://dx.doi.org/10.1016/j.jsb.2018.04.003 |