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Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC

We recently conducted a large association analysis to compare the genetic profiles between patients with psoriatic arthritis (PsA) and cutaneous-only psoriasis (PsC). Despite including over 7,000 genotyped patients, only the MHC achieved genome-wide significance. In this study, we hypothesized that...

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Detalles Bibliográficos
Autores principales: Patrick, Matthew T., Stuart, Philip E., Raja, Kalpana, Chi, Sunyi, He, Zhi, Voorhees, John J., Tejasvi, Trilokraj, Gudjonsson, Johann E., Kahlenberg, J. Michelle, Chandran, Vinod, Rahman, Proton, Gladman, Dafna D., Nair, Rajan P., Elder, James T., Tsoi, Lam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470186/
https://www.ncbi.nlm.nih.gov/pubmed/31031798
http://dx.doi.org/10.3389/fgene.2019.00304