Cargando…
Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC
We recently conducted a large association analysis to compare the genetic profiles between patients with psoriatic arthritis (PsA) and cutaneous-only psoriasis (PsC). Despite including over 7,000 genotyped patients, only the MHC achieved genome-wide significance. In this study, we hypothesized that...
Autores principales: | Patrick, Matthew T., Stuart, Philip E., Raja, Kalpana, Chi, Sunyi, He, Zhi, Voorhees, John J., Tejasvi, Trilokraj, Gudjonsson, Johann E., Kahlenberg, J. Michelle, Chandran, Vinod, Rahman, Proton, Gladman, Dafna D., Nair, Rajan P., Elder, James T., Tsoi, Lam C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470186/ https://www.ncbi.nlm.nih.gov/pubmed/31031798 http://dx.doi.org/10.3389/fgene.2019.00304 |
Ejemplares similares
-
TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis
por: Tejasvi, Trilokraj, et al.
Publicado: (2011) -
Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients
por: Patrick, Matthew T., et al.
Publicado: (2018) -
Quantifying Differences in Heritability among Psoriatic Arthritis (PsA), Cutaneous Psoriasis (PsC) and Psoriasis vulgaris (PsV)
por: Li, Quan, et al.
Publicado: (2020) -
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin
por: Tsoi, Lam C, et al.
Publicado: (2015) -
Complexities in Genetics of Psoriatic Arthritis
por: Rahmati, Sara, et al.
Publicado: (2020)