NIH3T3 Directs Memory-Fated CTL Programming and Represses High Expression of PD-1 on Antitumor CTLs

Memory CD8(+) T cells have long been considered a promising population for adoptive cell therapy (ACT) due to their long-term persistence and robust re-stimulatory response. NIH3T3 is an immortalized mouse embryonic fibroblast cell line. We report that NIH3T3-conditioned medium (CM) can augment effe...

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Detalles Bibliográficos
Autores principales: Qin, Yingyu, Lee, Yuna, Seo, Jaeho, Kim, Taehyun, Shin, Jung Hoon, Park, Se-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470252/
https://www.ncbi.nlm.nih.gov/pubmed/31031760
http://dx.doi.org/10.3389/fimmu.2019.00761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470252/
https://www.ncbi.nlm.nih.gov/pubmed/31031760
http://dx.doi.org/10.3389/fimmu.2019.00761

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