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Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells

Recently, a subpopulation of tumor cells, called cancer stem cells (CSC), has been characterized, and these have emerged as a major topic in cancer research. CSC are proposed to repair DNA damage more efficiently than the rest of tumor cells, resisting chemotherapy or radiotherapy and causing clinic...

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Detalles Bibliográficos
Autores principales: Valencia-González, Heriberto Abraham, Ruíz, Graciela, Ortiz-Sánchez, Elizabeth, García-Carrancá, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470433/
https://www.ncbi.nlm.nih.gov/pubmed/31073313
http://dx.doi.org/10.1155/2019/7038953