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Anti-PD-1 Antibody Administration following Hip Fracture Surgery Reverses Immune Dysfunction and Decreases Susceptibility to Infection

The aim of this investigation was to assess expression of programmed death-1 (PD-1) and inflammatory status after hip fracture surgery in aged mice and to evaluate the effect of anti-PD-1 antibody intervention. Male C57BL/6 mice aged 22-28 months underwent hip fracture and femoral intramedullary pin...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Chen, Chuying, He, Jiusheng, Zhang, Jianzheng, Liu, Zhi, Sun, Tiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470458/
https://www.ncbi.nlm.nih.gov/pubmed/31073275
http://dx.doi.org/10.1155/2019/8492090