An Improved Method for the Quaternization of Nicotinamide and Antifungal Activities of Its Derivatives

The quaternization reactions of nicotinamide, with different electrophiles: methyl iodide and substituted 2-bromoacetophenones (4-Cl, 4-Br, 4-H, 4-CH(3), 4-F, 4-OCH(3), 4-Ph, 2-OCH(3), 4-NO(2)) are reported. The preparations were carried out by conventional synthesis and under microwave irradiation...

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Detalles Bibliográficos
Autores principales: Siber, Tamara, Bušić, Valentina, Zobundžija, Dora, Roca, Sunčica, Vikić-Topić, Dražen, Vrandečić, Karolina, Gašo-Sokač, Dajana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470469/
https://www.ncbi.nlm.nih.gov/pubmed/30871137
http://dx.doi.org/10.3390/molecules24061001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470469/
https://www.ncbi.nlm.nih.gov/pubmed/30871137
http://dx.doi.org/10.3390/molecules24061001

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