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An Improved Method for the Quaternization of Nicotinamide and Antifungal Activities of Its Derivatives
The quaternization reactions of nicotinamide, with different electrophiles: methyl iodide and substituted 2-bromoacetophenones (4-Cl, 4-Br, 4-H, 4-CH(3), 4-F, 4-OCH(3), 4-Ph, 2-OCH(3), 4-NO(2)) are reported. The preparations were carried out by conventional synthesis and under microwave irradiation...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470469/ https://www.ncbi.nlm.nih.gov/pubmed/30871137 http://dx.doi.org/10.3390/molecules24061001 |