5-Iodo-4-thio-2′-Deoxyuridine as a Sensitizer of X-ray Induced Cancer Cell Killing

Nucleosides, especially pyrimidines modified in the C5-position, can act as radiosensitizers via a mechanism that involves their enzymatic triphosphorylation, incorporation into DNA, and a subsequent dissociative electron attachment (DEA) process. In this paper, we report 5-iodo-4-thio-2′-deoxyuridi...

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Detalles Bibliográficos
Autores principales: Makurat, Samanta, Spisz, Paulina, Kozak, Witold, Rak, Janusz, Zdrowowicz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470520/
https://www.ncbi.nlm.nih.gov/pubmed/30875879
http://dx.doi.org/10.3390/ijms20061308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470520/
https://www.ncbi.nlm.nih.gov/pubmed/30875879
http://dx.doi.org/10.3390/ijms20061308

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