‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency

Integrated venomics techniques have shown that variable processing of conotoxins from Conus marmoreus resulted in a dramatic expansion in the number of expressed conotoxins. One conotoxin from C. marmoreus, the χ-conotoxin MrIA, is a selective inhibitor of human norepinephrine transporters (hNET) an...

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Detalles Bibliográficos
Autores principales: Ziegman, Rebekah, Brust, Andreas, Jha, Prerna, Cardoso, Fernanda C., Lewis, Richard J., Alewood, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470548/
https://www.ncbi.nlm.nih.gov/pubmed/30875751
http://dx.doi.org/10.3390/md17030165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470548/
https://www.ncbi.nlm.nih.gov/pubmed/30875751
http://dx.doi.org/10.3390/md17030165

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