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Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario

Uncommon Epidermal Growth Factor Receptor (EGFR) mutations represent a distinct and highly heterogeneous subgroup of Non-Small Cell Lung Cancers (NSCLCs), that accounts for approximately 10% of all EGFR-mutated patients. The incidence of uncommon EGFR mutations is growing, due to the wider adoption...

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Detalles Bibliográficos
Autores principales: Russo, Alessandro, Franchina, Tindara, Ricciardi, Giuseppina, Battaglia, Alessandra, Picciotto, Maria, Adamo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470640/
https://www.ncbi.nlm.nih.gov/pubmed/30901844
http://dx.doi.org/10.3390/ijms20061431