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Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers

The quinoxaline scaffold is a promising platform for the discovery of active chemotherapeutic agents. Three series of quinoxaline derivatives were synthesized and biologically evaluated against three tumor cell lines (HCT116 human colon carcinoma, HepG2, liver hepatocellular carcinoma and MCF-7, hum...

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Detalles Bibliográficos
Autores principales: El Newahie, Aliya M. S., Nissan, Yassin M., Ismail, Nasser S. M., Abou El Ella, Dalal A., Khojah, Sohair M., Abouzid, Khaled A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470675/
https://www.ncbi.nlm.nih.gov/pubmed/30934622
http://dx.doi.org/10.3390/molecules24061175