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The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor?
The master mitotic regulator, Polo-like kinase 1 (Plk1), is an essential gene for the correct execution of cell division. Plk1 has strong clinical relevance, as it is considered a bona fide cancer target, it is found overexpressed in a large collection of different cancer types and this tumoral over...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470689/ https://www.ncbi.nlm.nih.gov/pubmed/30862113 http://dx.doi.org/10.3390/genes10030208 |