Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells

Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of therapeutics prepared by rational design of relatively short oligonucleotides to self-assemble into various programmab...

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Detalles Bibliográficos
Autores principales: Hong, Enping, Halman, Justin R., Shah, Ankit, Cedrone, Edward, Truong, Nguyen, Afonin, Kirill A., Dobrovolskaia, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470694/
https://www.ncbi.nlm.nih.gov/pubmed/30897721
http://dx.doi.org/10.3390/molecules24061094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470694/
https://www.ncbi.nlm.nih.gov/pubmed/30897721
http://dx.doi.org/10.3390/molecules24061094

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