Characterization of the High-Affinity Drug Ligand Binding Site of Mouse Recombinant TSPO

The optimization of translocator protein (TSPO) ligands for Positron Emission Tomography as well as for the modulation of neurosteroids is a critical necessity for the development of TSPO-based diagnostics and therapeutics of neuropsychiatrics and neurodegenerative disorders. Structural hints on the...

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Detalles Bibliográficos
Autores principales: Iatmanen-Harbi, Soria, Senicourt, lucile, Papadopoulos, Vassilios, Lequin, Olivier, Lacapere, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470738/
https://www.ncbi.nlm.nih.gov/pubmed/30901938
http://dx.doi.org/10.3390/ijms20061444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470738/
https://www.ncbi.nlm.nih.gov/pubmed/30901938
http://dx.doi.org/10.3390/ijms20061444

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