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Computational Drug Design Applied to the Study of Metabotropic Glutamate Receptors

Metabotropic glutamate (mGlu) receptors are a family of eight GPCRs that are attractive drug discovery targets to modulate glutamate action and response. Here we review the application of computational methods to the study of this family of receptors. X-ray structures of the extracellular and 7-tran...

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Detalles Bibliográficos
Autores principales: Llinas del Torrent, Claudia, Pérez-Benito, Laura, Tresadern, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470756/
https://www.ncbi.nlm.nih.gov/pubmed/30897742
http://dx.doi.org/10.3390/molecules24061098