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Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures

N-arachidonoyl glycine (NAGly) is an endocannabinoid involved in the regulation of different immune cells. It was shown to activate the GPR18 receptor, which was postulated to switch macrophages from cytotoxic to reparative. To study GPR18 expression and neuroprotection after NAGly treatment we used...

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Detalles Bibliográficos
Autores principales: Grabiec, Urszula, Hohmann, Tim, Ghadban, Chalid, Rothgänger, Candy, Wong, Daniel, Antonietti, Alexandra, Groth, Thomas, Mackie, Ken, Dehghani, Faramarz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470786/
https://www.ncbi.nlm.nih.gov/pubmed/30871175
http://dx.doi.org/10.3390/ijms20061266