Differential Methylation in APOE (Chr19; Exon Four; from 44,909,188 to 44,909,373/hg38) and Increased Apolipoprotein E Plasma Levels in Subjects with Mild Cognitive Impairment

Background: Biomarkers are essential for identification of individuals at high risk of mild cognitive impairment (MCI) for potential prevention of dementia. We investigated DNA methylation in the APOE gene and apolipoprotein E (ApoE) plasma levels as MCI biomarkers in Colombian subjects with MCI and...

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Detalles Bibliográficos
Autores principales: Mancera-Páez, Oscar, Estrada-Orozco, Kelly, Mahecha, María Fernanda, Cruz, Francy, Bonilla-Vargas, Kely, Sandoval, Nicolás, Guerrero, Esneyder, Salcedo-Tacuma, David, Melgarejo, Jesús D., Vega, Edwin, Ortega-Rojas, Jenny, Román, Gustavo C., Pardo-Turriago, Rodrigo, Arboleda, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470812/
https://www.ncbi.nlm.nih.gov/pubmed/30897703
http://dx.doi.org/10.3390/ijms20061394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470812/
https://www.ncbi.nlm.nih.gov/pubmed/30897703
http://dx.doi.org/10.3390/ijms20061394

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