Obesity-Altered Adipose Stem Cells Promote ER(+) Breast Cancer Metastasis through Estrogen Independent Pathways

Adipose stem cells (ASCs) play an essential role in tumor microenvironments. These cells are altered by obesity (obASCs) and previous studies have shown that obASCs secrete higher levels of leptin. Increased leptin, which upregulates estrogen receptor alpha (ERα) and aromatase, enhances estrogen bio...

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Detalles Bibliográficos
Autores principales: Sabol, Rachel A., Beighley, Adam, Giacomelli, Paulina, Wise, Rachel M., Harrison, Mark A. A., O’Donnnell, Ben A., Sullivan, Brianne N., Lampenfeld, Jacob D., Matossian, Margarite D., Bratton, Melyssa R., Wang, Guangdi, Collins-Burow, Bridgette M., Burow, Matthew E., Bunnell, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470828/
https://www.ncbi.nlm.nih.gov/pubmed/30897853
http://dx.doi.org/10.3390/ijms20061419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470828/
https://www.ncbi.nlm.nih.gov/pubmed/30897853
http://dx.doi.org/10.3390/ijms20061419

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