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Attenuated Replication of Lassa Virus Vaccine Candidate ML29 in STAT-1(-/-) Mice
Lassa virus (LASV), a highly prevalent mammalian arenavirus endemic in West Africa, can cause Lassa fever (LF), which is responsible for thousands of deaths annually. LASV is transmitted to humans from naturally infected rodents. At present, there is not an effective vaccine nor treatment. The genet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470856/ https://www.ncbi.nlm.nih.gov/pubmed/30650607 http://dx.doi.org/10.3390/pathogens8010009 |