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Attenuated Replication of Lassa Virus Vaccine Candidate ML29 in STAT-1(-/-) Mice

Lassa virus (LASV), a highly prevalent mammalian arenavirus endemic in West Africa, can cause Lassa fever (LF), which is responsible for thousands of deaths annually. LASV is transmitted to humans from naturally infected rodents. At present, there is not an effective vaccine nor treatment. The genet...

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Detalles Bibliográficos
Autores principales: Johnson, Dylan M., Jokinen, Jenny D., Lukashevich, Igor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470856/
https://www.ncbi.nlm.nih.gov/pubmed/30650607
http://dx.doi.org/10.3390/pathogens8010009