Cargando…
Attenuated Replication of Lassa Virus Vaccine Candidate ML29 in STAT-1(-/-) Mice
Lassa virus (LASV), a highly prevalent mammalian arenavirus endemic in West Africa, can cause Lassa fever (LF), which is responsible for thousands of deaths annually. LASV is transmitted to humans from naturally infected rodents. At present, there is not an effective vaccine nor treatment. The genet...
Autores principales: | Johnson, Dylan M., Jokinen, Jenny D., Lukashevich, Igor S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470856/ https://www.ncbi.nlm.nih.gov/pubmed/30650607 http://dx.doi.org/10.3390/pathogens8010009 |
Ejemplares similares
-
Lassa Virus Vaccine Candidate ML29 Generates Truncated Viral RNAs Which Contribute to Interfering Activity and Attenuation
por: Johnson, Dylan M., et al.
Publicado: (2021) -
Transcriptome Analysis of Human Peripheral Blood Mononuclear Cells Exposed to Lassa Virus and to the Attenuated Mopeia/Lassa Reassortant 29 (ML29), a Vaccine Candidate
por: Zapata, Juan Carlos, et al.
Publicado: (2013) -
Advanced Vaccine Candidates for Lassa Fever
por: Lukashevich, Igor S.
Publicado: (2012) -
Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins
por: Wang, Min, et al.
Publicado: (2017) -
Lassa virus diversity and feasibility for universal prophylactic vaccine
por: Lukashevich, Igor S., et al.
Publicado: (2019)