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iNOS Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient ob/ob Mice

The role of extracellular matrix (ECM) remodeling in fibrosis progression in nonalcoholic fatty liver disease (NAFLD) is complex and dynamic, involving the synthesis and degradation of different ECM components, including tenascin C (TNC). The aim was to analyze the influence of inducible nitric oxid...

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Detalles Bibliográficos
Autores principales: Becerril, Sara, Rodríguez, Amaia, Catalán, Victoria, Ramírez, Beatriz, Unamuno, Xabier, Gómez-Ambrosi, Javier, Frühbeck, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470935/
https://www.ncbi.nlm.nih.gov/pubmed/30818874
http://dx.doi.org/10.3390/genes10030184