Cargando…

Transcriptome Profiling and Molecular Therapeutic Advances in Cystic Fibrosis: Recent Insights

In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene disrupt the capacity of the encoded protein to function as a channel to transport chloride ions and water across cell membranes. The consequences are deleterious, system-wide, and immensely vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Ideozu, Justin E., Zhang, Xi, McColley, Susanna, Levy, Hara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470978/
https://www.ncbi.nlm.nih.gov/pubmed/30813620
http://dx.doi.org/10.3390/genes10030180