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Transcriptome Profiling and Molecular Therapeutic Advances in Cystic Fibrosis: Recent Insights
In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene disrupt the capacity of the encoded protein to function as a channel to transport chloride ions and water across cell membranes. The consequences are deleterious, system-wide, and immensely vari...
Autores principales: | Ideozu, Justin E., Zhang, Xi, McColley, Susanna, Levy, Hara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470978/ https://www.ncbi.nlm.nih.gov/pubmed/30813620 http://dx.doi.org/10.3390/genes10030180 |
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