Transcriptomic Impact of IMA-08401, a Novel AHR Agonist Resembling Laquinimod, on Rat Liver

IMA-08401 (C2) is a novel aryl hydrocarbon receptor (AHR) agonist and selective AHR modulator (SAHRM) that is structurally similar to laquinimod (LAQ). Both compounds are converted to the AHR-active metabolite DELAQ (IMA-06201) in vivo. SAHRMs have been proposed as therapeutic options for various au...

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Detalles Bibliográficos
Autores principales: Prokopec, Stephenie D., Pohjanvirta, Raimo, Mahiout, Selma, Pettersson, Lars, Boutros, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471016/
https://www.ncbi.nlm.nih.gov/pubmed/30893768
http://dx.doi.org/10.3390/ijms20061370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471016/
https://www.ncbi.nlm.nih.gov/pubmed/30893768
http://dx.doi.org/10.3390/ijms20061370

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