Cohesin-Mediated Genome Architecture Does Not Define DNA Replication Timing Domains

3D genome organization is strongly predictive of DNA replication timing in mammalian cells. This work tested the extent to which loop-based genome architecture acts as a regulatory unit of replication timing by using an auxin-inducible system for acute cohesin ablation. Cohesin ablation in a populat...

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Detalles Bibliográficos
Autores principales: Oldach, Phoebe, Nieduszynski, Conrad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471042/
https://www.ncbi.nlm.nih.gov/pubmed/30836708
http://dx.doi.org/10.3390/genes10030196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471042/
https://www.ncbi.nlm.nih.gov/pubmed/30836708
http://dx.doi.org/10.3390/genes10030196

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