Suppression of the Ubiquitin Pathway by Small Molecule Binding to Ubiquitin Enhances Doxorubicin Sensitivity of the Cancer Cells

Development of inhibitors for ubiquitin pathway has been suggested as a promising strategy to treat several types of cancers, which has been showcased by recent success of a series of novel anticancer drugs based on inhibition of ubiquitin pathways. Although the druggability of enzymes in ubiquitin...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh, Ho, Minh, Kim, Kyungmin, Yun, Sun-Il, Mizar, Pushpak, Easton, James W., Lee, Seung Seo, Kim, Kyeong Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471062/
https://www.ncbi.nlm.nih.gov/pubmed/30893775
http://dx.doi.org/10.3390/molecules24061073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471062/
https://www.ncbi.nlm.nih.gov/pubmed/30893775
http://dx.doi.org/10.3390/molecules24061073

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