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Umbilical cord blood-derived Helios-positive regulatory T cells promote angiogenesis in acute lymphoblastic leukemia in mice via CCL22 and the VEGFA-VEGFR2 pathway

Regulatory T cells (Tregs) maintain immune homeostasis and modulate tumor-induced neovascularization. However, the mechanisms underlying the role of Tregs in acute lymphoblastic leukemia (ALL) remain to be elucidated. Helios, combined with forkhead box P3, is considered a suitable marker for discrim...

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Detalles Bibliográficos
Autores principales: Li, Xue, Li, Dong, Shi, Qing, Huang, Xiaoyang, Ju, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471064/
https://www.ncbi.nlm.nih.gov/pubmed/30896872
http://dx.doi.org/10.3892/mmr.2019.10074