CLE-10 from Carpesium abrotanoides L. Suppresses the Growth of Human Breast Cancer Cells (MDA-MB-231) In Vitro by Inducing Apoptosis and Pro-Death Autophagy Via the PI3K/Akt/mTOR Signaling Pathway

Background: The antitumor activity of CLE-10 (4-epi-isoinuviscolide), a sesquiterpene lactone compound, isolated from Carpesium abrotanoides L. has rarely been reported. The aim of this study is to investigate the antitumor activity of CLE-10 and give a greater explanation of its underlying mechanis...

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Detalles Bibliográficos
Autores principales: Tian, Li, Cheng, Fan, Wang, Lei, Qin, Wen, Zou, Kun, Chen, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471079/
https://www.ncbi.nlm.nih.gov/pubmed/30897708
http://dx.doi.org/10.3390/molecules24061091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471079/
https://www.ncbi.nlm.nih.gov/pubmed/30897708
http://dx.doi.org/10.3390/molecules24061091

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