Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation

The monocarbonyl analogue of curcumin (1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one (C1) has been used as a specific activator of the master gene transcription factor EB (TFEB) to correlate the activation of this nuclear factor with the increased activity of lysosomal glycohydrolases and thei...

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Detalles Bibliográficos
Autores principales: Magini, Alessandro, Polchi, Alice, Di Meo, Danila, Buratta, Sandra, Chiaradia, Elisabetta, Germani, Raimondo, Emiliani, Carla, Tancini, Brunella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471159/
https://www.ncbi.nlm.nih.gov/pubmed/30889901
http://dx.doi.org/10.3390/ijms20061363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471159/
https://www.ncbi.nlm.nih.gov/pubmed/30889901
http://dx.doi.org/10.3390/ijms20061363

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