Physalis peruviana-Derived 4β-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo

Deregulation of the Wnt signaling pathway leads to colorectal cancer progression. Natural dietary compounds serve as promising candidates for development as chemopreventive agents by suppressing the Wnt/β-catenin signaling pathway. Physalis peruviana-derived 4βHWE showed a significant inhibitory act...

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Detalles Bibliográficos
Autores principales: Ye, Zhen-Nan, Yuan, Feng, Liu, Jie-Qing, Peng, Xing-Rong, An, Tao, Li, Xue, Kong, Ling-Mei, Qiu, Ming-Hua, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471161/
https://www.ncbi.nlm.nih.gov/pubmed/30909473
http://dx.doi.org/10.3390/molecules24061146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471161/
https://www.ncbi.nlm.nih.gov/pubmed/30909473
http://dx.doi.org/10.3390/molecules24061146

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