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Physalis peruviana-Derived 4β-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo
Deregulation of the Wnt signaling pathway leads to colorectal cancer progression. Natural dietary compounds serve as promising candidates for development as chemopreventive agents by suppressing the Wnt/β-catenin signaling pathway. Physalis peruviana-derived 4βHWE showed a significant inhibitory act...
Autores principales: | Ye, Zhen-Nan, Yuan, Feng, Liu, Jie-Qing, Peng, Xing-Rong, An, Tao, Li, Xue, Kong, Ling-Mei, Qiu, Ming-Hua, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471161/ https://www.ncbi.nlm.nih.gov/pubmed/30909473 http://dx.doi.org/10.3390/molecules24061146 |
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