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HDAC Inhibitors: Therapeutic Potential in Fibrosis-Associated Human Diseases

Fibrosis is characterized by excessive deposition of the extracellular matrix and develops because of fibroblast differentiation during the process of inflammation. Various cytokines stimulate resident fibroblasts, which differentiate into myofibroblasts. Myofibroblasts actively synthesize an excess...

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Detalles Bibliográficos
Autores principales: Yoon, Somy, Kang, Gaeun, Eom, Gwang Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471162/
https://www.ncbi.nlm.nih.gov/pubmed/30884785
http://dx.doi.org/10.3390/ijms20061329