Modular Enzymatic Cascade Synthesis of Vitamin B(5) and Its Derivatives

Access to vitamin B(5) [(R)‐pantothenic acid] and both diastereoisomers of α‐methyl‐substituted vitamin B(5) [(R)‐ and (S)‐3‐((R)‐2,4‐dihydroxy‐3,3‐dimethylbutanamido)‐2‐methylpropanoic acid] was achieved using a modular three‐step biocatalytic cascade involving 3‐methylaspartate ammonia lyase (MAL)...

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Detalles Bibliográficos
Autores principales: Abidin, Mohammad Z., Saravanan, Thangavelu, Zhang, Jielin, Tepper, Pieter G., Strauss, Erick, Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471175/
https://www.ncbi.nlm.nih.gov/pubmed/30192043
http://dx.doi.org/10.1002/chem.201804151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471175/
https://www.ncbi.nlm.nih.gov/pubmed/30192043
http://dx.doi.org/10.1002/chem.201804151

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