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Modular Enzymatic Cascade Synthesis of Vitamin B(5) and Its Derivatives
Access to vitamin B(5) [(R)‐pantothenic acid] and both diastereoisomers of α‐methyl‐substituted vitamin B(5) [(R)‐ and (S)‐3‐((R)‐2,4‐dihydroxy‐3,3‐dimethylbutanamido)‐2‐methylpropanoic acid] was achieved using a modular three‐step biocatalytic cascade involving 3‐methylaspartate ammonia lyase (MAL)...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471175/ https://www.ncbi.nlm.nih.gov/pubmed/30192043 http://dx.doi.org/10.1002/chem.201804151 |